node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
def | fmt | HMPREF9021_01798 | HMPREF9021_00637 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.911 |
def | rplD | HMPREF9021_01798 | HMPREF9021_01623 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.864 |
def | rplQ | HMPREF9021_01798 | HMPREF9021_01619 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L17. | 0.932 |
def | rplU | HMPREF9021_01798 | HMPREF9021_01534 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.854 |
def | rplV | HMPREF9021_01798 | HMPREF9021_01627 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.954 |
def | rpsF | HMPREF9021_01798 | HMPREF9021_00713 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.877 |
def | rpsJ | HMPREF9021_01798 | HMPREF9021_01595 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.889 |
def | rpsP | HMPREF9021_01798 | HMPREF9021_01096 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.856 |
def | rpsT | HMPREF9021_01798 | HMPREF9021_00964 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.859 |
def | tig | HMPREF9021_01798 | HMPREF9021_00986 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.850 |
fmt | def | HMPREF9021_00637 | HMPREF9021_01798 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.911 |
fmt | rplU | HMPREF9021_00637 | HMPREF9021_01534 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.406 |
fmt | rpsJ | HMPREF9021_00637 | HMPREF9021_01595 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.417 |
rplD | def | HMPREF9021_01623 | HMPREF9021_01798 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.864 |
rplD | rplQ | HMPREF9021_01623 | HMPREF9021_01619 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L17. | 0.996 |
rplD | rplU | HMPREF9021_01623 | HMPREF9021_01534 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.994 |
rplD | rplV | HMPREF9021_01623 | HMPREF9021_01627 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.999 |
rplD | rpsF | HMPREF9021_01623 | HMPREF9021_00713 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.993 |
rplD | rpsJ | HMPREF9021_01623 | HMPREF9021_01595 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
rplD | rpsP | HMPREF9021_01623 | HMPREF9021_01096 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.993 |