STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1EDQ3_HELROUncharacterized protein. (355 aa)    
Predicted Functional Partners:
T1EM18_HELRO
RNase H domain-containing protein.
  
  
 0.710
T1G012_HELRO
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
   
    0.672
T1FG73_HELRO
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
  
 0.626
T1G3A6_HELRO
Uncharacterized protein.
   
 
 0.605
T1EEC6_HELRO
Uncharacterized protein.
   
  
 0.572
T1G0Y7_HELRO
Uncharacterized protein.
    
 0.572
T1G4I2_HELRO
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
      
 0.557
T1G9E5_HELRO
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
  
  
 0.492
T1G7X7_HELRO
Uncharacterized protein.
  
  
 0.490
T1EDL6_HELRO
NAD(P)-bd_dom domain-containing protein.
  
    0.472
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.