STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1EFZ6_HELROPresenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (586 aa)    
Predicted Functional Partners:
T1FSB4_HELRO
Ncstrn_small domain-containing protein.
   
 0.993
T1G9Q4_HELRO
Uncharacterized protein.
   
 0.990
T1G7F6_HELRO
Uncharacterized protein.
    
 0.989
T1EEE9_HELRO
Uncharacterized protein.
    
 0.946
T1FR17_HELRO
Uncharacterized protein.
    
 0.946
T1G0U1_HELRO
Uncharacterized protein.
    
 0.922
T1G6P3_HELRO
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
  
  
 
0.903
T1EF50_HELRO
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.679
T1ELY5_HELRO
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
     
 0.679
T1EMJ9_HELRO
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.679
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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