STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1EGV2_HELROSET domain-containing protein. (369 aa)    
Predicted Functional Partners:
T1G0U5_HELRO
Uncharacterized protein.
   
 0.706
T1EDW3_HELRO
WD_REPEATS_REGION domain-containing protein.
   
 0.645
T1FN14_HELRO
WD_REPEATS_REGION domain-containing protein.
    
 0.636
T1FNB7_HELRO
B30.2/SPRY domain-containing protein.
    
 0.636
T1EMC3_HELRO
WD_REPEATS_REGION domain-containing protein.
   
 0.619
T1EE77_HELRO
P53 domain-containing protein.
   
 0.617
T1EZJ4_HELRO
Uncharacterized protein.
   
 0.617
T1F526_HELRO
JmjC domain-containing protein.
   
 0.608
T1FNP8_HELRO
PCI domain-containing protein.
    
 0.560
T1F5Y5_HELRO
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.541
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.