node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
T1EDR1_HELRO | T1EJC6_HELRO | T1EDR1 | T1EJC6 | SHMT domain-containing protein. | Uncharacterized protein. | 0.690 |
T1EDR1_HELRO | T1FGC2_HELRO | T1EDR1 | T1FGC2 | SHMT domain-containing protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.471 |
T1EDR1_HELRO | T1FGF1_HELRO | T1EDR1 | T1FGF1 | SHMT domain-containing protein. | DALR_1 domain-containing protein. | 0.471 |
T1EDR1_HELRO | T1FNT6_HELRO | T1EDR1 | T1FNT6 | SHMT domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.471 |
T1EDR1_HELRO | T1FNV9_HELRO | T1EDR1 | T1FNV9 | SHMT domain-containing protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.471 |
T1EJC6_HELRO | T1EDR1_HELRO | T1EJC6 | T1EDR1 | Uncharacterized protein. | SHMT domain-containing protein. | 0.690 |
T1EJC6_HELRO | T1EMB4_HELRO | T1EJC6 | T1EMB4 | Uncharacterized protein. | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | 0.698 |
T1EJC6_HELRO | T1FGC2_HELRO | T1EJC6 | T1FGC2 | Uncharacterized protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.699 |
T1EJC6_HELRO | T1FGF1_HELRO | T1EJC6 | T1FGF1 | Uncharacterized protein. | DALR_1 domain-containing protein. | 0.699 |
T1EJC6_HELRO | T1FNT6_HELRO | T1EJC6 | T1FNT6 | Uncharacterized protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.699 |
T1EJC6_HELRO | T1FNV9_HELRO | T1EJC6 | T1FNV9 | Uncharacterized protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.699 |
T1EJC6_HELRO | T1FW18_HELRO | T1EJC6 | T1FW18 | Uncharacterized protein. | ENDO3c domain-containing protein. | 0.720 |
T1EJC6_HELRO | T1FXF4_HELRO | T1EJC6 | T1FXF4 | Uncharacterized protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.868 |
T1EJC6_HELRO | T1G4X4_HELRO | T1EJC6 | T1G4X4 | Uncharacterized protein. | Uncharacterized protein. | 0.852 |
T1EJC6_HELRO | T1G841_HELRO | T1EJC6 | T1G841 | Uncharacterized protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.879 |
T1EMB4_HELRO | T1EJC6_HELRO | T1EMB4 | T1EJC6 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | Uncharacterized protein. | 0.698 |
T1FGC2_HELRO | T1EDR1_HELRO | T1FGC2 | T1EDR1 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | SHMT domain-containing protein. | 0.471 |
T1FGC2_HELRO | T1EJC6_HELRO | T1FGC2 | T1EJC6 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Uncharacterized protein. | 0.699 |
T1FGC2_HELRO | T1FNT6_HELRO | T1FGC2 | T1FNT6 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.919 |
T1FGC2_HELRO | T1FNV9_HELRO | T1FGC2 | T1FNV9 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.901 |