STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1EM25_HELROUncharacterized protein; Belongs to the LDH/MDH superfamily. (332 aa)    
Predicted Functional Partners:
T1EFL7_HELRO
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.968
T1EM15_HELRO
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.968
T1G3A5_HELRO
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.968
T1ELV3_HELRO
Aspartate aminotransferase.
   
 0.966
T1EMJ5_HELRO
Aminotran_1_2 domain-containing protein.
   
 0.965
T1G9W0_HELRO
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.964
T1EF05_HELRO
Malic enzyme.
  
 0.948
T1FP82_HELRO
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.934
T1ELL0_HELRO
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.933
T1G9N6_HELRO
Transket_pyr domain-containing protein.
  
 0.933
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.