STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1F4Z5_HELROUncharacterized protein. (636 aa)    
Predicted Functional Partners:
T1EY34_HELRO
Uncharacterized protein.
   
 
 0.909
T1EF66_HELRO
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
   
  
 0.776
T1FQV4_HELRO
Flavodoxin-like domain-containing protein.
   
 
 0.775
T1G896_HELRO
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
   
  
 0.769
T1FWU8_HELRO
SAM-dependent MTase TRM10-type domain-containing protein.
   
  
 0.761
T1FZ94_HELRO
SAM-dependent MTase TRM10-type domain-containing protein.
   
  
 0.761
T1FXC4_HELRO
TRUD domain-containing protein.
   
  
 0.760
T1G9E5_HELRO
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
  
  
 0.757
T1G7F0_HELRO
FtsJ domain-containing protein.
   
 
 0.753
T1EMH6_HELRO
tRNA (guanine(26)-N(2))-dimethyltransferase.
   
  
 0.752
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.