STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1FMU3_HELROPCI domain-containing protein. (454 aa)    
Predicted Functional Partners:
T1EDG5_HELRO
PCI domain-containing protein.
   
 0.999
T1EE33_HELRO
Proteasome subunit alpha type.
   
 0.999
T1EFQ2_HELRO
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 0.999
T1EKI3_HELRO
Proteasome subunit alpha type.
   
 0.999
T1ELJ7_HELRO
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.999
T1ELT0_HELRO
Uncharacterized protein.
   
 0.999
T1ELX3_HELRO
PCI domain-containing protein.
   
 0.999
T1ELY7_HELRO
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.999
T1EYD7_HELRO
Proteasome subunit beta.
   
 0.999
T1FM20_HELRO
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.999
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
Server load: low (26%) [HD]