STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1FNV7_HELROATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (340 aa)    
Predicted Functional Partners:
T1EPB6_HELRO
Uncharacterized protein.
    
 0.998
T1G296_HELRO
Uncharacterized protein.
    
 0.997
T1FNF7_HELRO
Uncharacterized protein.
   
 0.958
T1FPU1_HELRO
RING-type domain-containing protein.
   
 0.906
T1FNI5_HELRO
t-SNARE coiled-coil homology domain-containing protein.
   
 0.835
T1ED36_HELRO
TPR_REGION domain-containing protein.
   
 0.811
T1FMZ5_HELRO
Ubiquitin-like domain-containing protein.
    
 0.806
T1FM88_HELRO
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.765
T1G7X1_HELRO
Uncharacterized protein; Belongs to the synaptobrevin family.
   
 
 0.753
T1ESJ8_HELRO
Uncharacterized protein.
  
 
 0.702
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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