STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1FP82_HELRO2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (443 aa)    
Predicted Functional Partners:
T1ELL0_HELRO
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
T1G9N6_HELRO
Transket_pyr domain-containing protein.
 0.999
T1FM96_HELRO
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.998
T1FM91_HELRO
Dihydrolipoyl dehydrogenase.
  
 
 0.997
T1FZH5_HELRO
Uncharacterized protein.
  
 
 0.988
T1G421_HELRO
Lipoyl-binding domain-containing protein.
  
 0.970
T1EFC1_HELRO
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.954
T1FN89_HELRO
Uncharacterized protein; Belongs to the TPP enzyme family.
  
 
 0.942
T1EV62_HELRO
2-oxoacid_dh domain-containing protein.
  
 0.940
T1FZM3_HELRO
Lipoyl-binding domain-containing protein.
  
 0.940
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.