STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1FRG7_HELROSF4 helicase domain-containing protein. (767 aa)    
Predicted Functional Partners:
T1G5H7_HELRO
Uncharacterized protein.
   
  
 0.688
T1ED15_HELRO
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
  
 0.641
T1EY16_HELRO
Uncharacterized protein.
      
 0.596
T1EKH7_HELRO
Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance; Belongs to the MGME1 family.
      
 0.562
T1FHA3_HELRO
Dna2 domain-containing protein.
      
 0.560
T1EM18_HELRO
RNase H domain-containing protein.
      
 0.558
T1FA09_HELRO
DNApol_Exo domain-containing protein.
   
  
 0.558
T1FU49_HELRO
POLAc domain-containing protein.
   
  
 0.558
T1ELD3_HELRO
DUF155 domain-containing protein.
      
 0.555
T1EDF7_HELRO
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.549
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
Server load: low (24%) [HD]