STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1FSI6_HELROUncharacterized protein. (1468 aa)    
Predicted Functional Partners:
T1FDH4_HELRO
Uncharacterized protein.
    
 0.928
T1G485_HELRO
Uncharacterized protein.
   
 0.919
T1G4X7_HELRO
Uncharacterized protein.
   
 0.914
T1G9E1_HELRO
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.779
T1EMB0_HELRO
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.749
T1EES6_HELRO
BRCT domain-containing protein.
    
 
 0.516
T1FRW9_HELRO
Uncharacterized protein.
    
 
 0.516
T1G6D3_HELRO
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 
 0.458
T1ED73_HELRO
PX domain-containing protein.
      
 0.448
T1FRE5_HELRO
Uncharacterized protein.
    
 
 0.445
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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