STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1FV92_HELROUncharacterized protein. (565 aa)    
Predicted Functional Partners:
T1G956_HELRO
Poly [ADP-ribose] polymerase.
  
 
 0.672
T1F0W1_HELRO
ANK_REP_REGION domain-containing protein.
    
 0.583
T1FRS2_HELRO
Poly [ADP-ribose] polymerase.
    
 0.583
T1FS51_HELRO
Poly [ADP-ribose] polymerase.
    
 0.583
T1FS52_HELRO
Uncharacterized protein.
    
 0.583
T1FSR8_HELRO
Poly [ADP-ribose] polymerase.
    
 0.583
T1FWB0_HELRO
Uncharacterized protein.
    
 0.583
T1FMB5_HELRO
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
   0.514
T1FYM7_HELRO
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
     
 0.478
T1EE23_HELRO
Uncharacterized protein.
     
 0.416
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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