STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1FWB0_HELROUncharacterized protein. (664 aa)    
Predicted Functional Partners:
T1EHV9_HELRO
Uncharacterized protein.
    
 0.770
T1FLA5_HELRO
Uncharacterized protein.
    
 0.770
T1FYM7_HELRO
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.747
T1FUD3_HELRO
VWFA domain-containing protein.
   
 
 0.734
T1FTR6_HELRO
Tower domain-containing protein.
    
 0.711
T1F304_HELRO
RPA_C domain-containing protein.
   
 0.706
T1FW84_HELRO
Uncharacterized protein.
    
 0.693
T1G286_HELRO
BHD_3 domain-containing protein.
    
 0.693
T1ELR5_HELRO
XPA_C domain-containing protein.
     
 0.684
T1G7I6_HELRO
TIMELESS domain-containing protein.
   
 
 0.679
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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