STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1FYV0_HELROUncharacterized protein. (187 aa)    
Predicted Functional Partners:
T1ELV2_HELRO
Uncharacterized protein.
    
 0.949
T1ED31_HELRO
Uncharacterized protein.
    
 0.936
T1EFH1_HELRO
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.931
T1F347_HELRO
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.913
T1FDK6_HELRO
SH3 domain-containing protein.
   
 0.802
T1G657_HELRO
Abi_HHR domain-containing protein.
   
 0.802
T1FP77_HELRO
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.686
T1G0V3_HELRO
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 0.617
T1FMT3_HELRO
Uncharacterized protein; Belongs to the actin family.
    
 0.594
T1FP32_HELRO
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
     
 0.589
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.