STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1G1E1_HELROTranscription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (107 aa)    
Predicted Functional Partners:
T1G671_HELRO
Uncharacterized protein.
   
 0.963
T1G1B4_HELRO
TFIIE beta domain-containing protein.
   
 0.962
T1G7S2_HELRO
HTH TFE/IIEalpha-type domain-containing protein.
    
 0.946
T1G378_HELRO
Uncharacterized protein.
   
 0.943
T1FM77_HELRO
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
    
 0.942
T1FME1_HELRO
General transcription factor IIH subunit.
   
 0.938
T1ETM3_HELRO
RNA_pol_L_2 domain-containing protein.
   
  0.929
T1EX11_HELRO
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
 0.927
T1FMV6_HELRO
Uncharacterized protein.
    
 0.927
T1ED87_HELRO
Uncharacterized protein.
    
 0.919
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.