STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
glnDUTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (935 aa)    
Predicted Functional Partners:
SES28849.1
Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family.
 
 
 0.951
SER52237.1
Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family.
 
 
 0.950
murJ
Putative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
 
   
 0.907
SER81803.1
ABC-type branched-chain amino acid transport system, substrate-binding protein.
       0.866
SES09801.1
Glutamate synthase (NADPH) large subunit.
     
 0.796
SER98517.1
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
 
   
 0.786
rsmI
16S rRNA (cytidine1402-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.731
SER81760.1
Putative endonuclease; Belongs to the UPF0102 family.
       0.731
SER44076.1
Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL.
  
 
 
 0.654
gshB
Glutathione synthase; Belongs to the prokaryotic GSH synthase family.
       0.621
Your Current Organism:
Roseivivax roseus
NCBI taxonomy Id: 641238
Other names: DSM 23042, KCTC 22650, R. roseus, Roseivivax roseus Zhang et al. 2014, Roseivivax sp. BH87090, strain BH87090
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