STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. (366 aa)    
Predicted Functional Partners:
SES37636.1
Signal transduction histidine kinase.
    
  0.909
SES37646.1
Hpt domain-containing protein.
    
  0.800
SER53662.1
PAS domain S-box-containing protein.
    
  0.782
SER99483.1
PAS domain S-box-containing protein.
    
  0.782
SES27829.1
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase.
       0.773
ribB
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.763
SES32418.1
Dihydroneopterin aldolase.
 
  
 0.758
SER68723.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.682
SES22359.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.682
SES32433.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.573
Your Current Organism:
Roseivivax roseus
NCBI taxonomy Id: 641238
Other names: DSM 23042, KCTC 22650, R. roseus, Roseivivax roseus Zhang et al. 2014, Roseivivax sp. BH87090, strain BH87090
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.