Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSATEP00000001015DNA topoisomerase II binding protein 1. (1485 aa)    
Predicted Functional Partners:
atrip
Uncharacterized protein.
    
 0.997
rhno1
Si:ch73-352p4.5.
    
 0.997
brca1
Uncharacterized protein.
   
 0.997
bard1
BRCA1 associated RING domain 1.
   
 0.996
ENSATEP00000009787
Uncharacterized protein.
    
 0.996
ticrr
Treslin_N domain-containing protein.
    
 
 0.996
CLSPN
Claspin.
   
 0.992
ENSATEP00000006306
BRCA1 interacting protein C-terminal helicase 1.
   
 0.989
RTEL1
Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]
   
 0.989
nbn
Nibrin.
    
 0.988
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
Server load: low (22%) [HD]