Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113156869Sulfotransferase; Belongs to the sulfotransferase 1 family. (292 aa)    
Predicted Functional Partners:
LOC113172448
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.869
dhcr7
7-dehydrocholesterol reductase.
     
 0.851
sts
Steroid sulfatase (microsomal), isozyme S.
   
 
 0.849
LOC113162806
Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
     
 0.846
ENSATEP00000011608
Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.
   
 
 0.844
ENSATEP00000012779
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
     
 0.841
LOC113156624
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 
 0.837
ENSATEP00000011761
Uncharacterized protein; Belongs to the cytochrome P450 family.
     
  0.835
ENSATEP00000022106
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
     
  0.835
dhcr24
24-dehydrocholesterol reductase.
     
  0.835
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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