Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
egr3Early growth response 3. (410 aa)    
Predicted Functional Partners:
LOC113155852
E1A binding protein p300 a.
    
 0.963
ENSATEP00000010634
E1A binding protein p300 b.
    
 0.963
LOC113155921
Early growth response 2b.
   
 0.942
ENSATEP00000034114
annotation not available
   
 0.942
ENSATEP00000009949
V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.
   
 0.925
LOC113161300
CREB binding protein a.
    
 0.925
LOC113168288
CREB binding protein b.
    
 0.925
ENSATEP00000028323
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.906
ENSATEP00000026005
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.893
LOC113162097
JunB proto-oncogene, AP-1 transcription factor subunit a.
   
 0.892
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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