Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (714 aa)    
Predicted Functional Partners:
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.990
ENSATEP00000005494
Epidermal growth factor.
    
 0.959
ENSATEP00000013458
Macrophage stimulating 1 receptor b.
    
 0.957
LOC113154399
Macrophage stimulating 1 receptor a.
    
 0.957
vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
     
 0.917
egfr
Receptor protein-tyrosine kinase.
     
 0.916
LOC113163507
Receptor protein-tyrosine kinase.
     
 0.916
flt1
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
     
 0.900
erbb2
Receptor protein-tyrosine kinase.
     
 0.897
ENSATEP00000004658
Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.
     
 0.896
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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