Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sirt5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (303 aa)    
Predicted Functional Partners:
sirt6
Sirtuin 6.
  
0.965
ENSATEP00000031689
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
  
0.960
sirt7
Sirtuin 7.
   
 0.957
LOC113165531
Si:dkey-103i16.6.
  
0.945
sirt3
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
  
0.944
sirt4
NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.
   
 
 0.940
ENSATEP00000017941
Deacetylase sirtuin-type domain-containing protein.
  
  
0.930
nadsyn1
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.912
nmnat2
Nicotinamide nucleotide adenylyltransferase 2.
   
 0.909
ENSATEP00000025282
Nicotinamide-nucleotide adenylyltransferase.
   
 0.909
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
Server load: low (34%) [HD]