Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113171847PKS_ER domain-containing protein. (224 aa)    
Predicted Functional Partners:
ei24
EI24 autophagy associated transmembrane protein.
     
  0.870
pigm
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.
    
  0.802
hsdl2
Hydroxysteroid dehydrogenase like 2.
  
 0.792
LOC113157451
Prostaglandin reductase 1.
 
 0.746
LOC113157450
Prostaglandin reductase 1.
 
 0.746
PTGR1
Prostaglandin reductase 1.
 
 0.743
ENSATEP00000028232
Aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase).
  
 0.715
mmut
Methylmalonyl CoA mutase.
    
   0.694
ptgr2
Prostaglandin reductase 2.
  
 0.687
ENSATEP00000028323
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.678
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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