Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
socs1Suppressor of cytokine signaling 1a. (205 aa)    
Predicted Functional Partners:
eloc
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.993
jak1
Tyrosine-protein kinase.
    
 0.980
socs2
Suppressor of cytokine signaling 2.
    
0.971
ENSATEP00000028323
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.969
ENSATEP00000001131
Tyrosine-protein kinase.
    
 0.968
LOC113156423
Suppressor of cytokine signaling 3.
   
 
0.968
jak3
Tyrosine-protein kinase.
    
 0.968
LOC113147780
Tyrosine-protein kinase.
    
 0.968
tyk2
Tyrosine-protein kinase.
    
 0.968
socs3
Suppressor of cytokine signaling 3a.
   
 
0.968
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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