Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
metMET proto-oncogene, receptor tyrosine kinase. (1420 aa)    
Predicted Functional Partners:
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.990
ENSATEP00000026456
Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.990
grb2
Growth factor receptor-bound protein 2b.
    
 0.983
gab1
GRB2-associated binding protein 1.
    
 0.979
LOC113157564
PH domain-containing protein.
    
 0.979
LOC113169632
Uncharacterized protein.
    
 0.976
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.976
ENSATEP00000016335
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.976
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
 0.968
ENSATEP00000003563
GRB2 related adaptor protein 2b.
    
 0.958
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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