| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSATEP00000005465 | ENSATEP00000028323 | ENSATEP00000005465 | ENSATEP00000028323 | Small ubiquitin-related modifier. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.910 |
| ENSATEP00000005465 | LOC113155638 | ENSATEP00000005465 | ENSATEP00000008982 | Small ubiquitin-related modifier. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.935 |
| ENSATEP00000005465 | LOC113173839 | ENSATEP00000005465 | ENSATEP00000002396 | Small ubiquitin-related modifier. | RAN binding protein 2. | 0.955 |
| ENSATEP00000005465 | pcna | ENSATEP00000005465 | ENSATEP00000029027 | Small ubiquitin-related modifier. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.925 |
| ENSATEP00000005465 | pias4 | ENSATEP00000005465 | ENSATEP00000035215 | Small ubiquitin-related modifier. | Protein inhibitor of activated STAT, 4a. | 0.974 |
| ENSATEP00000005465 | sae1 | ENSATEP00000005465 | ENSATEP00000007341 | Small ubiquitin-related modifier. | SUMO1 activating enzyme subunit 1. | 0.952 |
| ENSATEP00000005465 | smc5 | ENSATEP00000005465 | ENSATEP00000029572 | Small ubiquitin-related modifier. | AAA_23 domain-containing protein. | 0.908 |
| ENSATEP00000005465 | sumo1 | ENSATEP00000005465 | ENSATEP00000014337 | Small ubiquitin-related modifier. | Small ubiquitin-related modifier. | 0.948 |
| ENSATEP00000005465 | uba2 | ENSATEP00000005465 | ENSATEP00000013501 | Small ubiquitin-related modifier. | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | 0.947 |
| ENSATEP00000005465 | ube2i | ENSATEP00000005465 | ENSATEP00000022179 | Small ubiquitin-related modifier. | Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. | 0.935 |
| ENSATEP00000028323 | ENSATEP00000005465 | ENSATEP00000028323 | ENSATEP00000005465 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Small ubiquitin-related modifier. | 0.910 |
| ENSATEP00000028323 | LOC113155638 | ENSATEP00000028323 | ENSATEP00000008982 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.945 |
| ENSATEP00000028323 | LOC113173839 | ENSATEP00000028323 | ENSATEP00000002396 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | RAN binding protein 2. | 0.923 |
| ENSATEP00000028323 | pcna | ENSATEP00000028323 | ENSATEP00000029027 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.991 |
| ENSATEP00000028323 | pias4 | ENSATEP00000028323 | ENSATEP00000035215 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Protein inhibitor of activated STAT, 4a. | 0.979 |
| ENSATEP00000028323 | smc5 | ENSATEP00000028323 | ENSATEP00000029572 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | AAA_23 domain-containing protein. | 0.449 |
| ENSATEP00000028323 | sumo1 | ENSATEP00000028323 | ENSATEP00000014337 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Small ubiquitin-related modifier. | 0.998 |
| ENSATEP00000028323 | ube2i | ENSATEP00000028323 | ENSATEP00000022179 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. | 0.945 |
| LOC113155638 | ENSATEP00000005465 | ENSATEP00000008982 | ENSATEP00000005465 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Small ubiquitin-related modifier. | 0.935 |
| LOC113155638 | ENSATEP00000028323 | ENSATEP00000008982 | ENSATEP00000028323 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.945 |