Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSATEP00000005602Klotho. (974 aa)    
Predicted Functional Partners:
fgf23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.899
gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
    
 0.878
galm
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
 0.875
glb1
Galactosidase, beta 1; Belongs to the glycosyl hydrolase 35 family.
  
 
 0.855
ugdh
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
    
 0.855
ENSATEP00000000735
Alpha-galactosidase.
     
 0.854
FGFR1
Fibroblast growth factor receptor.
    
 0.852
rgn
Regucalcin.
    
  0.847
akr1a1
Aldo-keto reductase family 1, member A1b (aldehyde reductase).
    
 0.841
ENSATEP00000017034
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2.
    
 0.841
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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