Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)    
Predicted Functional Partners:
KYNU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
  
 
 0.994
ENSATEP00000001682
Indoleamine 2,3-dioxygenase 1.
   
 
 0.979
afmid
Arylformamidase.
  
 
 0.969
asmtl
Acetylserotonin O-methyltransferase-like.
    
 
 0.963
LOC113158180
Uncharacterized protein.
   
 
 0.961
TPH1
Tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a.
  
 
 0.933
tph2
Tryptophan hydroxylase 2 (tryptophan 5-monooxygenase).
  
 
 0.933
ENSATEP00000033138
Phenylalanine hydroxylase.
  
 
 0.917
ENSATEP00000016824
Ig-like domain-containing protein.
     
 0.902
ENSATEP00000024731
Histidine decarboxylase.
    
 0.900
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.