Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSATEP00000005939Niemann-Pick disease, type C1. (1245 aa)    
Predicted Functional Partners:
npc2
Niemann-Pick disease, type C2.
    
 0.988
srebf2
Sterol regulatory element binding transcription factor 2.
    
 0.895
srebf1
Sterol regulatory element binding transcription factor 1.
    
 0.885
OSBPL8
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.873
LOC113165320
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.873
insig2
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
    
 0.728
ENSATEP00000008344
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
    
 0.728
osbpl9
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.721
ENSATEP00000001046
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.712
OSBPL10
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.712
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.