Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ENSATEP00000006413Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)    
Predicted Functional Partners:
ENSATEP00000001303
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.932
lrp5
Low density lipoprotein receptor-related protein 5.
    
 0.932
ENSATEP00000029522
FZ domain-containing protein.
    
 0.932
ENSATEP00000003530
Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.929
ENSATEP00000006815
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.929
dkk1
Dickkopf WNT signaling pathway inhibitor 1a.
    
 0.929
fzd4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.928
ENSATEP00000016326
Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.928
ENSATEP00000032223
Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.928
LOC113161560
Uncharacterized protein.
    
 0.927
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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