Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cdc123Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family. (347 aa)    
Predicted Functional Partners:
eif2s2
Eukaryotic translation initiation factor 2, subunit 2 beta.
    
 
 0.976
eif2s3
Eukaryotic translation initiation factor 2, subunit 3 gamma.
    
 
 0.964
nudt5
Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.
   
 
 0.948
eif2s1
Eukaryotic translation initiation factor 2, subunit 1 alpha b.
   
 
 0.910
eefsec
Eukaryotic elongation factor, selenocysteine-tRNA-specific.
    
 
 0.808
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
    
 
 0.779
cops5
COP9 signalosome subunit 5.
   
   0.758
cdkal1
CDK5 regulatory subunit associated protein 1-like 1.
    
 
 0.743
cunh11orf58
Zgc:56106.
   
    0.736
mrps23
Mitochondrial ribosomal protein S23.
   
  
 0.729
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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