| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSATEP00000019205 | cdc45 | ENSATEP00000019205 | ENSATEP00000029649 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | CDC45 cell division cycle 45 homolog (S. cerevisiae). | 0.916 |
| ENSATEP00000019205 | cdc6 | ENSATEP00000019205 | ENSATEP00000030848 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
| ENSATEP00000019205 | mcm10 | ENSATEP00000019205 | ENSATEP00000006633 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | Minichromosome maintenance 10 replication initiation factor. | 0.996 |
| ENSATEP00000019205 | mcm2 | ENSATEP00000019205 | ENSATEP00000008167 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | DNA helicase; Belongs to the MCM family. | 0.995 |
| ENSATEP00000019205 | mcm3 | ENSATEP00000019205 | ENSATEP00000022916 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
| ENSATEP00000019205 | mcm4 | ENSATEP00000019205 | ENSATEP00000009913 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | DNA helicase; Belongs to the MCM family. | 0.994 |
| ENSATEP00000019205 | mcm5 | ENSATEP00000019205 | ENSATEP00000015989 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | DNA helicase; Belongs to the MCM family. | 0.994 |
| ENSATEP00000019205 | mcm6 | ENSATEP00000019205 | ENSATEP00000005985 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | DNA helicase; Belongs to the MCM family. | 0.994 |
| ENSATEP00000019205 | mcm7 | ENSATEP00000019205 | ENSATEP00000002827 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
| ENSATEP00000019205 | orc2 | ENSATEP00000019205 | ENSATEP00000007747 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | Origin recognition complex, subunit 2. | 0.999 |
| cdc45 | ENSATEP00000019205 | ENSATEP00000029649 | ENSATEP00000019205 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.916 |
| cdc45 | cdc6 | ENSATEP00000029649 | ENSATEP00000030848 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.973 |
| cdc45 | mcm10 | ENSATEP00000029649 | ENSATEP00000006633 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Minichromosome maintenance 10 replication initiation factor. | 0.999 |
| cdc45 | mcm2 | ENSATEP00000029649 | ENSATEP00000008167 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc45 | mcm3 | ENSATEP00000029649 | ENSATEP00000022916 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc45 | mcm4 | ENSATEP00000029649 | ENSATEP00000009913 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc45 | mcm5 | ENSATEP00000029649 | ENSATEP00000015989 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc45 | mcm6 | ENSATEP00000029649 | ENSATEP00000005985 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc45 | mcm7 | ENSATEP00000029649 | ENSATEP00000002827 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
| cdc45 | orc2 | ENSATEP00000029649 | ENSATEP00000007747 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Origin recognition complex, subunit 2. | 0.989 |