Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spint1Serine peptidase inhibitor, Kunitz type 1 a. (509 aa)    
Predicted Functional Partners:
hgfac
HGF activator.
    
 0.945
LOC113174569
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix.
    
 0.776
ENSATEP00000029970
Uncharacterized protein.
    
 0.776
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.718
ENSATEP00000026456
Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.718
ENSATEP00000036162
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.718
msh2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.668
mlh1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
      
 0.655
LOC113167214
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.645
ENSATEP00000035554
Hepsin; Belongs to the peptidase S1 family.
    
 0.633
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
Server load: medium (58%) [HD]