Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
thop1Thimet oligopeptidase 1. (686 aa)    
Predicted Functional Partners:
ace
Angiotensin-converting enzyme.
     
 0.914
ENSATEP00000019465
Si:dkey-194e6.1.
     
 0.855
ENSATEP00000023481
Angiotensin-converting enzyme.
     
 0.855
ENSATEP00000003366
Neurotensin.
     
 0.809
LOC113148162
Neutral cholesterol ester hydrolase 1a.
    
 0.728
ENSATEP00000009253
Neutral cholesterol ester hydrolase 1a.
    
 0.728
LOC113174908
Arylacetamide deacetylase.
    
 0.728
NCEH1
Neutral cholesterol ester hydrolase 1.
    
 0.728
ENSATEP00000032453
Uncharacterized protein.
    
 0.728
mcm7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
  
 0.717
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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