Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
nr2f2Nuclear receptor subfamily 2, group F, member 2. (417 aa)    
Predicted Functional Partners:
yap1
Yes-associated protein 1.
   
 
 0.828
SOX18
SRY-box transcription factor 18.
    
 
 0.823
AXIN2
Axin 2.
      
 0.756
LOC113160882
Axin 2 (conductin, axil).
      
 0.756
LOC113149800
Hes-related family bHLH transcription factor with YRPW motif 2.
    
 
 0.735
irx3
Iroquois homeobox 3a.
    
 
 0.722
lyve1
Lymphatic vessel endothelial hyaluronic receptor 1a.
   
 0.703
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.683
vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
      
 0.661
fat4
FAT atypical cadherin 4.
      
 0.642
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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