Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSATEP00000007634Mitogen-activated protein kinase. (350 aa)    
Predicted Functional Partners:
LOC113154185
MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily.
   
 0.975
ENSATEP00000028323
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.956
ENSATEP00000022278
Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.
    
 0.954
MAP2K6
Mitogen-activated protein kinase kinase 6.
  
0.954
LOC113156070
Mitogen-activated protein kinase kinase 6.
  
0.953
LOC113153803
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
  
 
0.952
ENSATEP00000026005
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
    
 0.949
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
    
 0.946
LOC113167560
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
    
 0.941
CDC25B
Cell division cycle 25B.
    
 0.941
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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