Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CDK18Cyclin dependent kinase 18; Belongs to the protein kinase superfamily. (455 aa)    
Predicted Functional Partners:
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.881
CDC25B
Cell division cycle 25B.
   
 0.873
ccnh
Cyclin H; Belongs to the cyclin family.
    
 0.860
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
    
 0.854
cdc27
Cell division cycle 27.
    
 0.853
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.853
anapc1
Anaphase promoting complex subunit 1.
    
 0.841
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.840
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
    
 0.837
ENSATEP00000005055
Cyclin A1; Belongs to the cyclin family.
   
 0.828
Your Current Organism:
Anabas testudineus
NCBI taxonomy Id: 64144
Other names: A. testudineus, Amphiprion testudineus, Anthias testudineus, Antias testudineus, climbing perch
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