STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPR68896.1Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; Overlaps CDS with the same product name; overlaps another CDS with the same product name. (290 aa)    
Predicted Functional Partners:
EPR68835.1
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit.
 
 0.999
EPR68894.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.994
EPR68893.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.993
EPR68895.1
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; Overlaps CDS with the same product name; overlaps another CDS with the same product name.
     0.993
EPR67869.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.987
EPR68897.1
Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.
  0.970
EPR67486.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
  
  0.966
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.955
sucC
Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.906
EPR65051.1
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase; Dihydrolipoamide dehydrogenase.
 
  0.889
Your Current Organism:
Cyclobacterium qasimii
NCBI taxonomy Id: 641524
Other names: C. qasimii M12-11B, Cyclobacterium qasimii M12-11B, Cyclobacterium sp. M12-11B
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