STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiCUnannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (655 aa)    
Predicted Functional Partners:
GCA_002104455_00088
Unannotated protein.
 
 0.999
thiG
Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.987
GCA_002104455_00090
Unannotated protein.
  
  
 0.926
GCA_002104455_00091
Unannotated protein.
 
  
 0.842
GCA_002104455_01677
Unannotated protein.
 
  
 0.746
GCA_002104455_02315
Unannotated protein.
  
  
 0.700
purM
Unannotated protein.
     
 0.653
purC
Unannotated protein; Belongs to the SAICAR synthetase family.
    
 0.602
bioB
Unannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
  
 0.567
bioD
Unannotated protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
  
 0.492
Your Current Organism:
Colwellia chukchiensis
NCBI taxonomy Id: 641665
Other names: C. chukchiensis, CGMCC 1.9127, Colwellia chukchiensis Yu et al. 2011, Colwellia sp. BCw111, DSM 22576, LMG 25329, LMG:25329, strain BCw111
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