STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDD73441.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (131 aa)    
Predicted Functional Partners:
SDE11862.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase.
 
 
 0.988
SDE51793.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.986
folE-2
GTP cyclohydrolase I.
 
 
 0.902
folE
GTP cyclohydrolase I.
 
 
 0.891
SDE92494.1
Dihydrofolate synthase / folylpolyglutamate synthase.
  
 
 0.755
SDD73412.1
Type IX secretion system membrane protein, PorP/SprF family.
       0.673
SDD73315.1
Gliding motility-associated C-terminal domain-containing protein.
       0.606
SDD73338.1
Type IX secretion system membrane protein, PorP/SprF family.
       0.606
SDD73369.1
Gliding motility-associated C-terminal domain-containing protein.
       0.606
SDE66520.1
XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.580
Your Current Organism:
Pricia antarctica
NCBI taxonomy Id: 641691
Other names: DSM 23421, JCM 17291, Maribacter sp. ZS1-8, P. antarctica, Pricia antarctica Yu et al. 2012, strain ZS1-8
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