node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDE08137.1 | SDE29190.1 | SAMN05421636_103174 | SAMN05421636_104249 | Cystathionine beta-synthase. | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.483 |
SDE08137.1 | SDE29220.1 | SAMN05421636_103174 | SAMN05421636_104250 | Cystathionine beta-synthase. | Serine O-acetyltransferase. | 0.949 |
SDE08137.1 | SDE90885.1 | SAMN05421636_103174 | SAMN05421636_108262 | Cystathionine beta-synthase. | Aspartate kinase. | 0.918 |
SDE08137.1 | SDE90910.1 | SAMN05421636_103174 | SAMN05421636_108263 | Cystathionine beta-synthase. | O-acetylhomoserine sulfhydrylase. | 0.800 |
SDE08137.1 | cysS | SAMN05421636_103174 | SAMN05421636_105380 | Cystathionine beta-synthase. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.894 |
SDE08137.1 | glyA | SAMN05421636_103174 | SAMN05421636_104120 | Cystathionine beta-synthase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.806 |
SDE08137.1 | thrB | SAMN05421636_103174 | SAMN05421636_107300 | Cystathionine beta-synthase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.783 |
SDE08137.1 | trpA | SAMN05421636_103174 | SAMN05421636_108121 | Cystathionine beta-synthase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.782 |
SDE08137.1 | trpB | SAMN05421636_103174 | SAMN05421636_108120 | Cystathionine beta-synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.769 |
SDE29190.1 | SDE08137.1 | SAMN05421636_104249 | SAMN05421636_103174 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cystathionine beta-synthase. | 0.483 |
SDE29190.1 | SDE29220.1 | SAMN05421636_104249 | SAMN05421636_104250 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine O-acetyltransferase. | 0.999 |
SDE29190.1 | SDE61917.1 | SAMN05421636_104249 | SAMN05421636_106151 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cystathionine beta-synthase. | 0.481 |
SDE29190.1 | SDE90885.1 | SAMN05421636_104249 | SAMN05421636_108262 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aspartate kinase. | 0.918 |
SDE29190.1 | SDE90910.1 | SAMN05421636_104249 | SAMN05421636_108263 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | O-acetylhomoserine sulfhydrylase. | 0.556 |
SDE29190.1 | cysS | SAMN05421636_104249 | SAMN05421636_105380 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.943 |
SDE29190.1 | glyA | SAMN05421636_104249 | SAMN05421636_104120 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.477 |
SDE29190.1 | thrB | SAMN05421636_104249 | SAMN05421636_107300 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.417 |
SDE29190.1 | trpA | SAMN05421636_104249 | SAMN05421636_108121 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.412 |
SDE29220.1 | SDE08137.1 | SAMN05421636_104250 | SAMN05421636_103174 | Serine O-acetyltransferase. | Cystathionine beta-synthase. | 0.949 |
SDE29220.1 | SDE29190.1 | SAMN05421636_104250 | SAMN05421636_104249 | Serine O-acetyltransferase. | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.999 |