SDE34528.1 protein (Pricia antarctica) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

SDE34528.1

Nucleotide-binding universal stress protein, UspA family. (274 aa)

Predicted Functional Partners:

SDE48405.1

0.728

SDE34714.1

0.698

SDE34839.1

0.673

SDE48980.1

0.592

SDE48295.1

0.554

SDE34678.1

0.553

SDE48622.1

0.550

SDD88995.1

0.518

SDD88434.1

0.484

SDE44431.1

0.452

Your Current Organism:

Pricia antarctica

NCBI taxonomy Id: 641691
Other names: DSM 23421, JCM 17291, Maribacter sp. ZS1-8, P. antarctica, Pricia antarctica Yu et al. 2012, strain ZS1-8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDD88434.1	SDD88995.1	SAMN05421636_102214	SAMN05421636_102234	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.722
SDD88434.1	SDE34528.1	SAMN05421636_102214	SAMN05421636_104424	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.484
SDD88995.1	SDD88434.1	SAMN05421636_102234	SAMN05421636_102214	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.722
SDD88995.1	SDE34528.1	SAMN05421636_102234	SAMN05421636_104424	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.518
SDE34528.1	SDD88434.1	SAMN05421636_104424	SAMN05421636_102214	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.484
SDE34528.1	SDD88995.1	SAMN05421636_104424	SAMN05421636_102234	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.518
SDE34528.1	SDE34678.1	SAMN05421636_104424	SAMN05421636_104428	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.553
SDE34528.1	SDE34714.1	SAMN05421636_104424	SAMN05421636_104429	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.698
SDE34528.1	SDE34839.1	SAMN05421636_104424	SAMN05421636_104433	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.673
SDE34528.1	SDE44431.1	SAMN05421636_104424	SAMN05421636_10589	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.452
SDE34528.1	SDE48295.1	SAMN05421636_104424	SAMN05421636_105230	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.554
SDE34528.1	SDE48405.1	SAMN05421636_104424	SAMN05421636_105234	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.728
SDE34528.1	SDE48622.1	SAMN05421636_104424	SAMN05421636_105241	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.550
SDE34528.1	SDE48980.1	SAMN05421636_104424	SAMN05421636_105254	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.592
SDE34678.1	SDE34528.1	SAMN05421636_104428	SAMN05421636_104424	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.553
SDE34678.1	SDE34714.1	SAMN05421636_104428	SAMN05421636_104429	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.541
SDE34714.1	SDE34528.1	SAMN05421636_104429	SAMN05421636_104424	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.698
SDE34714.1	SDE34678.1	SAMN05421636_104429	SAMN05421636_104428	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.541
SDE34839.1	SDE34528.1	SAMN05421636_104433	SAMN05421636_104424	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.673
SDE44431.1	SDE34528.1	SAMN05421636_10589	SAMN05421636_104424	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.452

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Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.79

expected number of edges:

15

PPI enrichment p-value:

0.00497

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009225

Nucleotide-sugar metabolic process

5 of 18

2.06

3.06

3.16e-07

GO:0019305

dTDP-rhamnose biosynthetic process

3 of 3

2.62

2.4

3.54e-05

GO:0000271

Polysaccharide biosynthetic process

8 of 107

1.49

2.34

2.70e-08

GO:0009226

Nucleotide-sugar biosynthetic process

4 of 16

2.01

2.31

1.69e-05

GO:0009243

O antigen biosynthetic process

2 of 2

2.62

1.44

0.0023

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008831

dTDP-4-dehydrorhamnose reductase activity

2 of 2

2.62

0.89

0.0246

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4145

O-Antigen nucleotide sugar biosynthesis, and SIS domain

9 of 18

2.32

7.11

1.10e-16

CL:4146

Polyketide sugar unit biosynthesis, and GDP-mannose metabolic process

7 of 10

2.46

6.2

1.97e-13

CL:4148

Polyketide sugar unit biosynthesis

5 of 5

2.62

4.71

8.85e-10

CL:4140

Mixed, incl. Polysaccharide biosynthetic process, and Amino sugar and nucleotide sugar metabolism

10 of 158

1.42

2.61

5.40e-12

CL:4139

Mixed, incl. Polysaccharide biosynthetic process, and Nucleotide-diphospho-sugar transferases

11 of 194

1.37

2.55

2.34e-13

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

mdn00541

O-Antigen nucleotide sugar biosynthesis

8 of 25

2.12

5.58

5.09e-14

mdn00523

Polyketide sugar unit biosynthesis

5 of 5

2.62

4.9

3.67e-10

mdn00521

Streptomycin biosynthesis

5 of 11

2.27

4.08

4.21e-09

mdn00525

Acarbose and validamycin biosynthesis

2 of 2

2.62

1.72

0.00069

mdn00520

Amino sugar and nucleotide sugar metabolism

3 of 37

1.53

1.24

0.0015

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01370

NAD dependent epimerase/dehydratase family

3 of 14

1.95

1.18

0.0050

PF13727

CoA-binding domain

2 of 4

2.32

0.94

0.0189

PF02397

Bacterial sugar transferase

2 of 3

2.44

0.94

0.0189

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