STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPG7Spastic paraplegia 7. (783 aa)    
Predicted Functional Partners:
VDAC1
Voltage-dependent anion-selective channel protein 1 isoform X1.
   
 0.932
MAIP1
M-AAA protease-interacting protein 1, mitochondrial.
    
 0.897
PHB2
Prohibitin 2.
   
 0.886
VDAC2
Voltage-dependent anion-selective channel protein 2 isoform X1.
   
 0.881
PHB-2
Prohibitin 1.
   
 0.880
PHB
Prohibitin-like isoform X1.
   
 0.880
VDAC3
Voltage-dependent anion-selective channel protein 3 isoform X1.
   
 0.879
ADAM10
Disintegrin and metalloproteinase domain-containing protein 10.
     
 0.853
AFG3L2
AFG3-like protein 2 isoform X1.
  
 
0.834
ENSPMRP00000014118
annotation not available
  
 
0.834
Your Current Organism:
Podarcis muralis
NCBI taxonomy Id: 64176
Other names: Common wall lizard, Lacerrta muralis, Mauereidechse, P. muralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.