STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECW1E3 ubiquitin-protein ligase HECW1 isoform X1. (1601 aa)    
Predicted Functional Partners:
RPS27A
Ribosomal protein S27a.
    
 0.805
ENSPMRP00000034826
LOW QUALITY PROTEIN: polyubiquitin-C-like.
    
 0.758
UBB
Ubiquitin B.
    
 0.758
PSMD4
26S proteasome non-ATPase regulatory subunit 4.
    
 0.754
UBA52
Ubiquitin-large subunit ribosomal protein L40e.
    
 0.747
SMAD7
Mothers against decapentaplegic homolog 7 isoform X1.
    
 0.679
SMAD6
Mothers against decapentaplegic homolog 6.
    
 0.679
ENSPMRP00000024675
Mothers against decapentaplegic homolog 6-like.
    
 0.679
ENSPMRP00000020511
annotation not available
    
 0.655
SMAD4
Mothers against decapentaplegic homolog 4 isoform X1.
   
 0.643
Your Current Organism:
Podarcis muralis
NCBI taxonomy Id: 64176
Other names: Common wall lizard, Lacerrta muralis, Mauereidechse, P. muralis
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