STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BACE2Beta-site APP-cleaving enzyme 2 (memapsin 1). (522 aa)    
Predicted Functional Partners:
APP
Amyloid-beta precursor protein isoform X1.
    
 0.785
AKAP3
A-kinase anchor protein 3 isoform X1.
      
 0.657
GGA1
ADP-ribosylation factor-binding protein GGA1.
    
 0.636
GGA2
ADP-ribosylation factor-binding protein GGA2 isoform X1.
    
 0.636
APLP2
Amyloid-like protein 2 isoform X1.
    
 0.569
MITF
Microphthalmia-associated transcription factor isoform X1.
     
 0.539
APLP1
Amyloid-like protein 1 isoform X1.
    
 0.535
SORCS1
VPS10 domain-containing receptor SorCS1 isoform X1.
    
 
 0.525
TMEM130
Transmembrane protein 130.
      
 0.474
IDE
Insulin-degrading enzyme isoform X1.
     
 0.421
Your Current Organism:
Podarcis muralis
NCBI taxonomy Id: 64176
Other names: Common wall lizard, Lacerrta muralis, Mauereidechse, P. muralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.