STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HUWE1E3 ubiquitin-protein ligase HUWE1 isoform X1. (4385 aa)    
Predicted Functional Partners:
MCL1
MCL1 apoptosis regulator, BCL2 family member.
    
 
 0.929
UBA52
Ubiquitin-large subunit ribosomal protein L40e.
    
 0.889
DDIT4
DNA damage-inducible transcript 4 protein.
    
   0.874
RPS27A
Ribosomal protein S27a.
   
 0.853
TRIP12
LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIP12.
   
 
0.837
ENSPMRP00000034826
LOW QUALITY PROTEIN: polyubiquitin-C-like.
   
 0.826
UBB
Ubiquitin B.
   
 0.826
ZBTB17
Zinc finger and BTB domain-containing protein 17 isoform X1.
    
 
 0.816
ENSPMRP00000020511
annotation not available
    
 0.811
TRRAP
Transformation/transcription domain-associated protein.
   
 
 0.752
Your Current Organism:
Podarcis muralis
NCBI taxonomy Id: 64176
Other names: Common wall lizard, Lacerrta muralis, Mauereidechse, P. muralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.