STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
ADZ84676.1Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (537 aa)    
Predicted Functional Partners:
ADZ84677.1
KEGG: cpr:CPR_1641 phosphocarrier protein (HPr); TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein; PFAM: Phosphotransferase system, phosphocarrier HPr protein.
 
 0.999
ADZ84619.1
KEGG: ttm:Tthe_0766 phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein; PFAM: Phosphotransferase system, phosphocarrier HPr protein.
 
 0.997
ADZ83851.1
PFAM: Phosphotransferase system, phosphocarrier HPr protein; KEGG: eel:EUBELI_01159 hypothetical protein.
  
 0.981
ADZ82058.1
PTS system, glucose subfamily, IIA subunit; TIGRFAM: Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system, glucose-like IIB component; KEGG: cbt:CLH_3174 PTS system, glucose-like IIB component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site.
 
 0.980
ADZ82929.1
PTS system, glucose subfamily, IIA subunit; TIGRFAM: Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system, glucose-like IIB component; KEGG: cbt:CLH_3174 PTS system, glucose-like IIB component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site.
 
 0.980
ADZ85524.1
PTS system, fructose subfamily, IIC subunit; KEGG: cbt:CLH_2044 heat-responsive suppressor HrsA; TIGRFAM: Phosphotransferase system, fructose IIC component; Phosphotransferase system, IIA component fructose subfamily; Phosphotransferase system, fructose-specific IIB subunit; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; Phosphotransferase system, EIIC; Phosphotransferase system, EIIB component, type 2/3.
 
  
 0.977
ADZ85602.1
TIGRFAM: Phosphotransferase system, beta-glucoside-specific IIABC component; Phosphotransferase system, sugar-specific permease EIIA 1 domain; KEGG: cbb:CLD_3685 PTS system, beta-glucoside-specific, IIABC component; PFAM: Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site; Phosphotransferase system, EIIC.
 
 0.964
ADZ85523.1
TIGRFAM: 1-phosphofructokinase; Tagatose/fructose phosphokinase; KEGG: cbk:CLL_A2297 1-phosphofructokinase; PFAM: Carbohydrate/purine kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.829
ADZ82498.1
KEGG: cbk:CLL_A0331 pts system, IIBC component; TIGRFAM: Phosphotransferase system, IIBC component; Phosphotransferase system, glucose-like IIB component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site.
  
 0.756
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
 
   
 0.736
Your Current Organism:
Cellulosilyticum lentocellum
NCBI taxonomy Id: 642492
Other names: C. lentocellum DSM 5427, Cellulosilyticum lentocellum DSM 5427, Clostridium lentocellum ATCC 49066, Clostridium lentocellum DSM 5427, Clostridium lentocellum str. DSM 5427, Clostridium lentocellum strain DSM 5427
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