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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ84902.1PFAM: Inosine monophosphate cyclohydrolase-like; KEGG: ere:EUBREC_1566 hypothetical protein. (235 aa)    
Predicted Functional Partners:
ADZ84901.1
Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; KEGG: ere:EUBREC_1567 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain.
 
  
 0.990
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.908
ADZ85908.1
PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; KEGG: elm:ELI_1158 IMP dehydrogenase; SMART: Cystathionine beta-synthase, core.
     
 0.906
ADZ82370.1
KEGG: sad:SAAV_0686 hypothetical protein.
     
  0.900
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
  0.900
ADZ83625.1
TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: tte:TTE2394 hypoxanthine-guanine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
ADZ85073.1
TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: bpb:bpr_I2906 hypoxanthine phosphoribosyltransferase Hpt; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
      0.887
ADZ83191.1
TIGRFAM: Phosphoribosylformylglycinamidine synthase, FGAM; KEGG: cac:CA_C1655 bifunctional phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein.
  
  
 0.623
purD
Phosphoribosylamine/glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; KEGG: elm:ELI_1205 hypothetical protein; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family.
  
  
 0.443
Your Current Organism:
Cellulosilyticum lentocellum
NCBI taxonomy Id: 642492
Other names: C. lentocellum DSM 5427, Cellulosilyticum lentocellum DSM 5427, Clostridium lentocellum ATCC 49066, Clostridium lentocellum DSM 5427, Clostridium lentocellum str. DSM 5427, Clostridium lentocellum strain DSM 5427
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