STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_0314Sigma 54 interacting domain protein; COGs: COG1067 ATP-dependent protease; InterProIPR002078:IPR003593:IPR008268:IPR001984:IPR 020568:IPR003959:IPR008269:IPR014251; KEGG: hor:Hore_14920 sporulation protease LonB; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; PRIAM: Endopeptidase La; SMART: AAA ATPase; SPTR: B8CY72 Sporulation protease LonB; TIGRFAM: ATP-dependent protease LonB; PFAM: ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease LonB; lon-related putative AT [...] (556 aa)    
Predicted Functional Partners:
Slip_0415
Sporulation stage III protein AB; InterPro IPR014198; KEGG: swo:Swol_0551 hypothetical protein; PFAM: Sporulation stage III protein AB; SPTR: Q0AZG9 Putative uncharacterized protein; PFAM: Stage III sporulation protein AB (spore_III_AB); TIGRFAM: stage III sporulation protein AB.
  
    0.802
Slip_0418
Stage III sporulation protein AE; InterPro IPR014194; KEGG: swo:Swol_0554 hypothetical protein; PFAM: Sporulation stage III protein AE; SPTR: Q0AZG6 Putative uncharacterized protein; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE.
  
    0.668
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.657
Slip_0491
Stage II sporulation protein M; InterPro IPR014196:IPR018062:IPR002798; KEGG: swo:Swol_0605 uncharacterized membrane protein; PFAM: protein of unknown function DUF95 transmembrane; SPTR: Q0AZC0 Uncharacterized membrane protein; TIGRFAM: stage II sporulation protein M; PFAM: Integral membrane protein DUF95; TIGRFAM: stage II sporulation protein M.
  
    0.618
Slip_1332
Protein of unknown function DUF2600; InterPro IPR019712; KEGG: dau:Daud_1265 hypothetical protein; PFAM: Protein of unknown function DUF2600; SPTR: B1I412 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2600).
  
     0.618
Slip_0417
Stage III sporulation protein AD; InterPro IPR014211; KEGG: swo:Swol_0553 putative sporulation protein; PFAM: Sporulation stage III protein AD; SPTR: Q0AZG7 Putative sporulation protein; TIGRFAM: stage III sporulation protein AD; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AD.
  
    0.612
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
  
 0.608
Slip_1658
KEGG: mta:Moth_0580 hypothetical protein; SPTR: Q2RKX9 Putative uncharacterized protein; PFAM: Membrane protein of unknown function.
  
     0.590
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  
0.585
engB
Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
       0.550
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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